I do tend to stick with established pairings - you can do that in fanfiction - such as Ron/Hermione, Shepard/Liara, Dante/Trish and so forth. I did break Hsrry and Ginny up, largely because Harry never turned out to be who Ginny wanted him to be. I invented a couple - Wolverine/Storm and Lily Potter/Scorpius Malfoy. I think the only OC romance I wrote was a lesbian one (in Flight of the 'Vigilant').
Most of the relationships in my stories are established before the tale starts, so I don't have to write romantic scenes, which I'm terrible at!