Evolved as a tool-using animal, with the enhanced dexterity and intelligence that requires, we are still subject to the biological imperative to pass our genes to the next generation.
It is that drive which creates our behaviour. It demands we survive, and our survival was contingent upon acquisition of knowledge and development of skills. But like all evolutionary processes, it is incomplete and imperfect. The same process that developed the massive herbivores and awesome predators of prehistory, only for them to die out in favour of species with more manageable adaptations, has led to the growth of an intelligence far beyond what is necessary for bare or even comfortable survival.
This in turn drives us to seek understanding of the world and ourselves. Some seek it in the imagination - story and art -this we call religion or spirituality. Others seek it by examination, exploration and experiment, this is science.
Imagination gives us absolutes. In this context, Great Cthulhu and the Flying Spaghetti Monster are no less valid than God. They are all products of the same faculty.
Science gives us evidence-based constructs we call theories, which can then be deconstructed or amended by further or contradictory evidence. As our ability to look deeper and further develops, so the evidence accrues and the theories change. This process might very well be infinite, as the Universe itself is subject to change and evolution. There may indeed be no final answer.
Regarding moral and ethical choices, these are entirely separate from both imagination and science. They are about the way we live and interact together, and the only guidance we need is the good of the community and the individuals who form it.